Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceALRNVPFRSEV-C
    • Amino acids2 to 12

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SLP76 antibody (ab17029)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • 76 kDa tyrosine phosphoprotein
    • CG8697
    • LCP 2
    • LCP2
    • LCP2_HUMAN
    • Lymphocyte cytosolic protein 2
    • SH2 domain containing leukocyte protein 76 KD
    • SH2 domain containing leukocyte protein of 76kD
    • SH2 domain containing leukocyte protein of 76kDa
    • SH2 domain-containing leukocyte protein of 76 kDa
    • SLP 76
    • SLP 76 tyrosine phosphoprotein
    • SLP-76
    • SLP-76 tyrosine phosphoprotein
    • SLP76
    • SLP76 tyrosine phosphoprotein
    see all
  • FunctionInvolved in T-cell antigen receptor mediated signaling.
  • Tissue specificityHighly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.
  • Sequence similaritiesContains 1 SAM (sterile alpha motif) domain.
    Contains 1 SH2 domain.
  • DomainThe SH2 domain mediates interaction with SHB.
  • Post-translational
    modifications
    Phosphorylated after T-cell receptor activation by ZAP-70.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human SLP76 peptide (ab45592)

ab45592 has not yet been referenced specifically in any publications.

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