Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      ATPYVPVPMPIGN-C
    • Amino acids
      2 to 14

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SNX16 antibody (ab4151)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • DKFZp666H147
    • OTTHUMP00000227313
    • OTTHUMP00000227314
    • SNX16
    • SNX16_HUMAN
    • Sorting nexin-16
    see all
  • Function
    May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
  • Tissue specificity
    Detected in placenta, lung, liver,heart and pancreas.
  • Sequence similarities
    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
  • Domain
    The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
  • Cellular localization
    Early endosome membrane. Late endosome membrane. Cytoplasm. Lysosome.
  • Information by UniProt

References

ab22994 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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