Overview

  • Product nameHuman SNX18 peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-KVQRVPLMTVLSF
    • Amino acids616 to 628

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SNX18 antibody (ab3941)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • FLJ11997
    • FLJ32560
    • FLJ61062
    • MGC150827
    • MGC150829
    • SH3 and PX domain containing protein 3B
    • SH3 and PX domain-containing protein 3B
    • SH3PX2
    • SH3PXD3B
    • SNAG 1
    • SNAG1
    • SNX18
    • SNX18_HUMAN
    • Sorting nexin 18
    • Sorting nexin associated golgi protein 1
    • Sorting nexin-18
    • Sorting nexin-associated Golgi protein 1
    see all
  • FunctionMay be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • Sequence similaritiesBelongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • DomainThe PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • Cellular localizationEndomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt

References for Human SNX18 peptide (ab22972)

ab22972 has not yet been referenced specifically in any publications.

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