Overview

  • Product name
    Human SORBS1 peptide

Description

  • Nature
    Synthetic
  • Source
    CHO cells
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-GTFPGNYVKPLYL

Associated products

Specifications

Our Abpromise guarantee covers the use of ab18388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SORBS1 antibody (ab4551)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • c-Cbl-associated protein
    • CAP
    • CBL Associated Protein
    • Ponsin
    • SH3 domain protein 5
    • SH3D5
    • SH3P12
    • Sorbin and SH3 Domain Containing 1
    • Sorbin and SH3 domain-containing protein 1
    • Sorbs1
    • SRBS1_HUMAN
    see all
  • Function
    Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
  • Tissue specificity
    Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
  • Sequence similarities
    Contains 3 SH3 domains.
    Contains 1 SoHo domain.
  • Post-translational
    modifications
    O-glycosylated.
  • Cellular localization
    Cell junction > adherens junction. Cell membrane. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
  • Information by UniProt

References

ab18388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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