Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-SYTNSHVEKDDLP
    • Amino acids602 to 614

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SSX2IP antibody (ab10256)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ADIP
    • ADIP_HUMAN
    • Afadin and alpha actinin binding protein
    • Afadin DIL domain interacting protein
    • Afadin DIL domain-interacting protein
    • Afadin- and alpha-actinin-binding protein
    • FLJ10848
    • KIAA0923
    • MGC75026
    • OTTHUMP00000011574
    • SSX 2 interacting protein
    • SSX2 interacting protein
    • SSX2-interacting protein
    • SSX2IP
    • Synovial sarcoma X breakpoint 2 interacting protein
    see all
  • FunctionBelongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin.
  • Tissue specificityWidely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen. All specific brain regions showed intermediate to high expression, with highest expression in amygdala. Also expressed in fetal tissues, mainly in liver and brain.
  • DomainBoth the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.
  • Cellular localizationCell junction > adherens junction. Nucleus. Not found at cell-matrix AJs.
  • Information by UniProt

References for Human SSX2IP peptide (ab23199)

ab23199 has not yet been referenced specifically in any publications.

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