For the best experience on the Abcam website please upgrade to a modern browser such as
Amino Acid Sequence
Sequence LSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Staufen antibody (
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Double stranded RNA binding protein Staufen homolog
Double stranded RNA binding protein Staufen homolog 1
Double-stranded RNA-binding protein Staufen homolog 1
Function Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Tissue specificity Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
Sequence similarities Contains 3 DRBM (double-stranded RNA-binding) domains.
Domain One of the DRDB could be involved in RER binding. The C-terminal contains the tubulin binding domain (TBD).
Cellular localization Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
Information by UniProt
References for Human Staufen peptide (ab111678)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"