Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab51555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TANK antibody (ab47632)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • I TRAF
    • I-TRAF
    • ITRAF
    • Tank
    • TANK_HUMAN
    • TRAF family member associated NF KAPPA B activator
    • TRAF family member associated NFKB activator
    • TRAF family member-associated NF-kappa-B activator
    • TRAF interacting protein
    • TRAF interacting protein TANK isoform a
    • TRAF interacting protein TANK isoform b
    • TRAF-interacting protein
    • TRAF2
    see all
  • FunctionActs as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 C2H2-type zinc finger.
  • Post-translational
    modifications
    Phosphorylated by IKBKE.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human TANK peptide (ab51555)

ab51555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"