Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab92908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TANK antibody (ab18819)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • I TRAF
    • I-TRAF
    • ITRAF
    • Tank
    • TANK_HUMAN
    • TRAF family member associated NF KAPPA B activator
    • TRAF family member associated NFKB activator
    • TRAF family member-associated NF-kappa-B activator
    • TRAF interacting protein
    • TRAF interacting protein TANK isoform a
    • TRAF interacting protein TANK isoform b
    • TRAF-interacting protein
    • TRAF2
    see all
  • FunctionActs as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 C2H2-type zinc finger.
  • Post-translational
    modifications
    Phosphorylated by IKBKE.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human TANK peptide (ab92908)

ab92908 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab92908.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"