Overview

  • Product nameHuman Tapasin protein fragment
  • DescriptionHuman Tapasin protein fragment

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionO15533
    • SpeciesHuman
    • SequencePGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEP WGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSL MPAT
    • Molecular weight37 kDa including tags
    • Amino acids197 to 300

Specifications

Our Abpromise guarantee covers the use of ab114877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional NotesProtein concentration is above or equal to 0.05 mg/ml
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General info

  • Alternative names
    • NGS 17
    • NGS-17
    • NGS17
    • TAP associated protein
    • TAP binding protein
    • TAP binding protein (tapasin)
    • TAP BP
    • TAP-associated protein
    • TAP-binding protein
    • TAPA
    • Tapasin
    • TAPBP
    • TPN
    • TPSN
    • TPSN_HUMAN
    see all
  • FunctionInvolved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • Tissue specificityNeutrophils, mostly in fully differentiated cells.
  • Sequence similaritiesContains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • DomainThe N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Target information above from: UniProt accession O15533 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Human Tapasin protein fragment images

  • 12.5% SDS-PAGE showing ab114877 at approximately 37.07kDa.
    Stained with Coomassie Blue.

References for Human Tapasin protein fragment (ab114877)

ab114877 has not yet been referenced specifically in any publications.

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