Overview

  • Product nameHuman TARBP1 peptide

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab42870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • FLJ30482
    • Probable methyltransferase TARBP1
    • TAR
    • TAR (HIV) RNA Binding Protein 1
    • TAR RNA Binding Protein 1
    • TAR RNA loop binding protein
    • TAR RNA-binding protein 1
    • TAR RNA-binding protein of 185 kDa
    • TARB1_HUMAN
    • TARBP1
    • TRM3
    • TRP-185
    • TRP185
    see all
  • FunctionProbable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
  • Sequence similaritiesBelongs to the RNA methyltransferase TrmH family.
  • Information by UniProt

References for Human TARBP1 peptide (ab42870)

ab42870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"