Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceSASDGSVCVLDLRK
    • Amino acids564 to 577

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TBL1 antibody (ab2243)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • EBI
    • F box like/WD repeat protein TBL1X
    • F-box-like/WD repeat-containing protein TBL1X
    • SMAP 55
    • SMAP55
    • TBL 1
    • TBL 1X
    • TBL1
    • TBL1X
    • TBL1X_HUMAN
    • Transducin (beta) like 1
    • Transducin (beta) like 1 X linked
    • Transducin (beta) like 1X linked
    • Transducin beta like 1 X linked
    • Transducin beta like 1X
    • Transducin beta like 1X protein
    • Transducin beta like protein 1, X linked
    • Transducin beta-like protein 1X
    • Transducin-beta-like protein 1
    • X-linked
    see all
  • FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the WD repeat EBI family.
    Contains 1 F-box-like domain.
    Contains 1 LisH domain.
    Contains 8 WD repeats.
  • DomainThe F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human TBL1 peptide (ab22881)

ab22881 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab22881.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"