Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceCAYKWLYDETLEDR
    • Amino acids383 to 396

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TFB2M antibody (ab13676)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Dimethyladenosine transferase 2
    • dimethyladenosine transferase 2 mitochondrial
    • FLJ22661
    • FLJ23182
    • h mtTFB
    • h mtTFB2
    • h-mtTFB
    • h-mtTFB2
    • HCV NS5A transactivated protein 5
    • HCV NS5A-transactivated protein 5
    • hepatitis C virus NS5A transactivated protein 5
    • Hepatitis C virus NS5A-transactivated protein 5
    • Hkp1
    • hTFB2M
    • mitochondrial
    • Mitochondrial 12S rRNA dimethylase 2
    • Mitochondrial dimethyladenosine transferase 2
    • Mitochondrial transcription factor B2
    • mtTFB
    • mtTFB2
    • N''-adenosyl(rRNA) dimethyltransferase 2
    • NS5ATP5
    • S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2
    • S-adenosylmethionine-6-N''
    • TFB2M
    • TFB2M_HUMAN
    • Transcription Factor B2
    • Transcription factor B2 mitochondrial
    see all
  • FunctionS-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
  • Tissue specificityUbiquitously expressed.
  • Sequence similaritiesBelongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • Cellular localizationMitochondrion.
  • Information by UniProt

References for Human TFB2M peptide (ab23228)

ab23228 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"