For the best experience on the Abcam website please upgrade to a modern browser such as
Amino Acid Sequence
Amino acids 292 to 304 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-TFPI antibody (
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Extrinsic pathway inhibitor
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Tissue specificity Mostly in endothelial cells.
Sequence similarities Contains 3 BPTI/Kunitz inhibitor domains.
Domain This inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa.
Post-translational modifications O-glycosylated.
Cellular localization Secreted.
Information by UniProt
References for Human TFPI peptide (ab23168)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"