Human Thromboxane synthase peptide (ab72365)

Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      TNPDCQEKLLREVDVFKEK
    • Amino acids
      359 to 377

Associated products

Specifications

Our Abpromise guarantee covers the use of ab72365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Thromboxane synthase antibody (ab39362)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

General Info

  • Alternative names
    • BDPLT14
    • CYP5
    • CYP5A1
    • Cytochrome P450 5A1
    • Cytochrome P450, family 5, subfamily A, polypeptide 1
    • FLJ52771
    • GHOSAL
    • Platelet cytochrome P450 subfamily V
    • Tbxas1
    • THAS
    • THAS_HUMAN
    • Thromboxane A synthase 1
    • Thromboxane A synthase 1 (platelet)
    • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
    • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V
    • Thromboxane-A synthase
    • TS
    • TXA synthase
    • TXAS
    • TXS
    see all
  • Tissue specificity
    Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
  • Involvement in disease
    Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
    Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt

References

ab72365 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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