Human Thromboxane synthase peptide (ab72365)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceTNPDCQEKLLREVDVFKEK
    • Amino acids359 to 377

Associated products

Specifications

Our Abpromise guarantee covers the use of ab72365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Thromboxane synthase antibody (ab39362)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

General Info

  • Alternative names
    • BDPLT14
    • CYP5
    • CYP5A1
    • Cytochrome P450 5A1
    • Cytochrome P450, family 5, subfamily A, polypeptide 1
    • FLJ52771
    • GHOSAL
    • Platelet cytochrome P450 subfamily V
    • Tbxas1
    • THAS
    • THAS_HUMAN
    • Thromboxane A synthase 1
    • Thromboxane A synthase 1 (platelet)
    • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
    • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V
    • Thromboxane-A synthase
    • TS
    • TXA synthase
    • TXAS
    • TXS
    see all
  • Tissue specificityPlatelets, lung, kidney, spleen, macrophages and lung fibroblasts.
  • Involvement in diseaseDefects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
    Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt

References for Human Thromboxane synthase peptide (ab72365)

ab72365 has not yet been referenced specifically in any publications.

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