Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab41475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TIA1 antibody (ab40693)

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Cytotoxic granule associated RNA binding protein
    • Cytotoxic granule associated RNA binding protein 1
    • mTIA-1
    • Nucleolysin TIA 1 isoform p40
    • Nucleolysin TIA-1 isoform p40
    • Nucleolysin TIA1 isoform p40
    • p40 TIA 1
    • p40-TIA-1
    • p40-TIA-1 (containing p15-TIA-1)
    • RNA binding protein TIA 1
    • RNA binding protein TIA1
    • RNA-binding protein TIA-1
    • T-cell-restricted intracellular antigen-1
    • Tia
    • TIA 1
    • TIA 1 cytotoxic granule associated RNA binding protein
    • TIA-1
    • TIA1
    • TIA1 cytotoxic granule associated RNA binding protein
    • TIA1 cytotoxic granule associated RNA binding protein like 1
    • TIA1 protein
    • TIA1_HUMAN
    • TIAL1
    • TIAR
    • WDM
    see all
  • FunctionInvolved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • Sequence similaritiesContains 3 RRM (RNA recognition motif) domains.
  • Cellular localizationCytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
  • Information by UniProt

References for Human TIA1 peptide (ab41475)

ab41475 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab41475.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"