Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab97423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TMEM16A antibody (ab84915)

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • ANO 1
    • ANO1
    • ANO1_HUMAN
    • Anoctamin 1
    • Anoctamin 1 calcium activated chloride channel
    • Anoctamin-1
    • Anoctamin1
    • Ca2+ activated Cl- channel
    • Calcium Activated Chloride Channel
    • Discovered on gastrointestinal stromal tumors protein 1
    • DOG 1
    • DOG1
    • FLJ10261
    • Membrane protein
    • Oral cancer overexpressed 2
    • Oral cancer overexpressed protein 2
    • ORAOV 2
    • ORAOV2
    • TAOS 2
    • TAOS2
    • TMEM 16A
    • TMEM16A
    • Transmembrane protein 16A
    • Transmembrane protein 16A (eight membrane spanning domains)
    • Tumor amplified and overexpressed sequence 2
    • Tumor-amplified and overexpressed sequence 2
    see all
  • Function
    Acts as a calcium-activated chloride channel. Required for normal tracheal development.
  • Tissue specificity
    Broadly expressed with higher levels in liver and skeletal muscle.
  • Sequence similarities
    Belongs to the anoctamin family.
  • Domain
    The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.
  • Cellular localization
    Cell membrane. Cytoplasm.
  • Information by UniProt

References

ab97423 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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