The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Src activating and signaling molecule
Src activating and signaling molecule protein
Src-activating and signaling molecule protein
Target of Myb like protein 1
Target of Myb-like protein 1
Target of myb1 (chicken) homolog like 1
Target of myb1 (chicken) like 1
Target of myb1 like 1
TOM1 like protein 1
TOM1-like protein 1
FunctionProbable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.
Sequence similaritiesBelongs to the TOM1 family. Contains 1 GAT domain. Contains 1 VHS domain.
Post-translational modificationsPhosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.