Ubiquitin conjugating enzyme 7 interacting protein 1
Zinc finger protein inhibiting NF kappa B
The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
References for Human TRIAD3 peptide (ab39886)
has not yet been referenced specifically in any publications.
Publishing research using ab39886? Please let us know so that we can cite the reference in this datasheet.
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