Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-EFTKKYGEKRPVD
    • Amino acids142 to 154

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Ube2L3 antibody (ab37913)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • E2 F1
    • L UBC
    • L-UBC
    • UB2L3_HUMAN
    • UBCE7
    • UbcH7
    • UbcM4
    • Ube2l3
    • Ubiquitin carrier protein L3
    • Ubiquitin conjugating enzyme E2 L3
    • Ubiquitin protein ligase L3
    • Ubiquitin-conjugating enzyme E2 L3
    • Ubiquitin-conjugating enzyme E2-F1
    • Ubiquitin-protein ligase L3
    see all
  • FunctionAccepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
  • Tissue specificityUbiquitous, with highest expression in testis.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the ubiquitin-conjugating enzyme family.
  • Post-translational
    modifications
    Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt

References for Human Ube2L3 peptide (ab45494)

ab45494 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"