Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-EQLKRELSKSRQ
    • Amino acids
      290 to 301

Specifications

Our Abpromise guarantee covers the use of ab48042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • mitochondrial brown fat uncoupling protein
    • Mitochondrial brown fat uncoupling protein 1
    • SLC25A7
    • Solute carrier family 25 member 7
    • Thermogenin
    • UCP
    • UCP 1
    • UCP1
    • UCP1_HUMAN
    • Uncoupling protein 1
    • uncoupling protein 1 (mitochondrial, proton carrier)
    see all
  • Function
    UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
  • Tissue specificity
    Brown adipose tissue.
  • Sequence similarities
    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt

References

ab48042 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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