The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-UCP1 antibody - Carboxyterminal end (ab47991)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
mitochondrial brown fat uncoupling protein
Mitochondrial brown fat uncoupling protein 1
Solute carrier family 25 member 7
Uncoupling protein 1
uncoupling protein 1 (mitochondrial, proton carrier)
FunctionUCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Tissue specificityBrown adipose tissue.
Sequence similaritiesBelongs to the mitochondrial carrier family. Contains 3 Solcar repeats.