Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      CSSPPSSEFMDVN
    • Amino acids
      909 to 921

Specifications

Our Abpromise guarantee covers the use of ab23087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Deubiquitinating enzyme 11
    • Ubiquitin carboxyl-terminal hydrolase 11
    • Ubiquitin carboxyl-terminal hydrolase X linked
    • ubiquitin specific peptidase 11
    • Ubiquitin specific protease 11
    • Ubiquitin thiolesterase 11
    • Ubiquitin-specific-processing protease 11
    • UBP11_HUMAN
    • UHX1
    • USP11
    see all
  • Function
    Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
  • Sequence similarities
    Belongs to the peptidase C19 family.
    Contains 1 DUSP domain.
  • Cellular localization
    Nucleus. Cytoplasm. Predominantly nuclear. Associates with chromatin.
  • Information by UniProt

References

ab23087 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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