The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-VPS29 antibody (ab10160)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Vacuolar protein sorting 29
Vacuolar protein sorting 29 (yeast homolog)
Vacuolar protein sorting 29 (yeast)
Vacuolar protein sorting 29 homolog
Vacuolar protein sorting 29 homolog (S. cerevisiae)
Vacuolar protein sorting associated protein 29
Vacuolar protein sorting-associated protein 29
Vacuolar sorting protein VPS29/PEP11
Vesicle protein sorting 29
x 007 protein
FunctionEssential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
Tissue specificityUbiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.