Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-DDVKVERIEYKKP
    • Amino acids
      170 to 182

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-VPS29 antibody (ab10160)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • DC15
    • DC7
    • DKFZp564F0223
    • FLJ20492
    • hVPS29
    • PEP11
    • PEP11 homolog
    • Retromer protein
    • Vacuolar protein sorting 29
    • Vacuolar protein sorting 29 (yeast homolog)
    • Vacuolar protein sorting 29 (yeast)
    • Vacuolar protein sorting 29 homolog
    • Vacuolar protein sorting 29 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 29
    • Vacuolar protein sorting-associated protein 29
    • Vacuolar sorting protein VPS29/PEP11
    • Vesicle protein sorting 29
    • VPS 29
    • VPS29
    • VPS29 retromer complex component
    • VPS29_HUMAN
    • x 007 protein
    see all
  • Function
    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
  • Tissue specificity
    Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
  • Sequence similarities
    Belongs to the VPS29 family.
  • Cellular localization
    Cytoplasm. Membrane. Endosome membrane.
  • Information by UniProt

References

ab23191 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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