The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Vacuolar protein sorting 33 homolog A
Vacuolar protein sorting 33 homolog A (S. cerevisiae)
Vacuolar protein sorting 33A
Vacuolar protein sorting 33A (rat homolog)
Vacuolar protein sorting 33A (yeast)
Vacuolar protein sorting associated protein 33A
RelevanceVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Cellular localizationLate endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note: Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
References for Human VPS33A peptide (ab23177)
has not yet been referenced specifically in any publications.
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