Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-SPESEGPIYEGLIL
    • Amino acids
      783 to 796

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-VPS35 antibody (ab10099)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • DKFZp434E1211
    • DKFZp434P1672
    • FLJ10752
    • FLJ13588
    • FLJ20388
    • hVPS35
    • Maternal embryonic 3
    • Maternal-embryonic 3
    • MEM 3
    • MEM3
    • PARK17
    • TCCCTA00141
    • Vacuolar protein sorting 35
    • Vacuolar protein sorting 35 (yeast)
    • Vacuolar protein sorting 35 homolog
    • Vacuolar protein sorting associated protein 35
    • Vacuolar protein sorting-associated protein 35
    • Vesicle protein sorting 35
    • VPS 35
    • VPS35
    • VPS35_HUMAN
    see all
  • Function
    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
  • Tissue specificity
    Ubiquitous. Highly expressed in heart, brain, placenta, skeletal muscle, spleen, thymus, testis, ovary, small intestine, kidney and colon.
  • Sequence similarities
    Belongs to the VPS35 family.
  • Cellular localization
    Cytoplasm. Membrane.
  • Information by UniProt

References

ab23181 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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