Overview

  • Product nameHuman WRCH1 peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequencePPQQGDPAFPDRCEA
    • Amino acids2 to 16

Specifications

Our Abpromise guarantee covers the use of ab23007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ARHU
    • CDC42 L1
    • CDC42 like GTPase
    • CDC42-like GTPase 1
    • CDC42L1
    • G28K
    • GTP binding protein like 1
    • GTP binding protein SB128
    • GTP-binding protein-like 1
    • hG28K
    • mG28K
    • Ras homolog gene family member U
    • Ras homolog gene family member U isoform CRA a
    • Ras like gene family member U
    • Rho GTPase like protein ARHU
    • Rho GTPase-like protein ARHU
    • Rho related GTP binding protein RhoU
    • Rho-related GTP-binding protein RhoU
    • Rhou
    • RHOU_HUMAN
    • Ryu GTPase
    • Wnt-1 responsive Cdc42 homolog 1
    • Wnt1 responsive Cdc42 homolog
    • WRCH 1
    • WRCH-1
    see all
  • FunctionActs upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
  • Tissue specificityUbiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
  • Cellular localizationCell membrane. Golgi apparatus membrane. Cell junction > focal adhesion. Cell projection > podosome. Localizes to podosomes in SRC-transformed cells.
  • Information by UniProt

References for Human WRCH1 peptide (ab23007)

ab23007 has not yet been referenced specifically in any publications.

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