Overview

  • Product name
    Human WRCH1 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      PPQQGDPAFPDRCEA
    • Amino acids
      2 to 16

Specifications

Our Abpromise guarantee covers the use of ab23007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ARHU
    • CDC42 L1
    • CDC42 like GTPase
    • CDC42-like GTPase 1
    • CDC42L1
    • G28K
    • GTP binding protein like 1
    • GTP binding protein SB128
    • GTP-binding protein-like 1
    • hG28K
    • mG28K
    • Ras homolog gene family member U
    • Ras homolog gene family member U isoform CRA a
    • Ras like gene family member U
    • Rho GTPase like protein ARHU
    • Rho GTPase-like protein ARHU
    • Rho related GTP binding protein RhoU
    • Rho-related GTP-binding protein RhoU
    • Rhou
    • RHOU_HUMAN
    • Ryu GTPase
    • Wnt-1 responsive Cdc42 homolog 1
    • Wnt1 responsive Cdc42 homolog
    • WRCH 1
    • WRCH-1
    see all
  • Function
    Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
  • Tissue specificity
    Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rho family.
  • Cellular localization
    Cell membrane. Golgi apparatus membrane. Cell junction > focal adhesion. Cell projection > podosome. Localizes to podosomes in SRC-transformed cells.
  • Information by UniProt

References for Human WRCH1 peptide (ab23007)

ab23007 has not yet been referenced specifically in any publications.

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