Biological descriptionAnti-inflammatory, antimalarial and antirheumatic agent. Inhibits toll-like receptor 9 (IC50 = 80 nM). Active in vivo.
Chemical name7-Chloro-4-[4-[N-ethyl-N-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline sulfate
Storage instructionsStore at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for Hydroxychloroquine sulfate (ab120827)
This product has been referenced in:
Franklin BS et al. Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria. Proc Natl Acad Sci U S A108:3689-94 (2011).
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