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Products:Neuroscience >> Neurotransmission >> Nitric Oxide >> NOS
Overview
Product name
Anti-iNOS antibody, prediluted
See all iNOS products (11) ...
Description
Rabbit polyclonal to iNOS, prediluted
Tested applications
IHC-Fr, IHC-Pmore details
Cross reactivity
Reacts with
Rat, Human
Predicted to work with
Mouse
Immunogen
Synthetic peptide (Mouse) (C terminal).
Positive control
Lung tissue slides.
Properties
Form
Prediluted
Storage instructions
Store at +4°C.
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Cellular metabolic process
Cancer >> Cancer Metabolism >> Response to hypoxia
Neuroscience >> Neurotransmission >> Nitric Oxide >> NOS
-
- iNOS antibody, prediluted (ab15326)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab15326 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
IHC-P
Application notes
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-Fr: Use at an assay dependent dilution (PMID 20187933).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Tissue specificity
Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
Sequence similarities
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Target information above from: UniProt accessionP35228
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- inducible antibody
- HEP NOS antibody
- HEP-NOS antibody
see all
Database links
- Entrez Gene: 4843 Human
- Entrez Gene: 18126 Mouse
- Entrez Gene: 24599 Rat
- Omim: 163730 Human
- SwissProt: P35228 Human
- SwissProt: P29477 Mouse
- SwissProt: Q06518 Rat
- Unigene: 709191 Human
see all
Anti-iNOS antibody, prediluted images:
- iNOS antibody, prediluted (ab15326)
Human lung stained with ab15326 in IHC paraffin fixed sections.
References for Anti-iNOS antibody, prediluted (ab15326)
This product has been referenced in:
- Maddahi A & Edvinsson L Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway. J Neuroinflammation 7:14 (2010). IHC-Fr; Rat.Read more (PubMed: 20187933) »
- Mishima Tet al. Chemopreventative effect of an inducible nitric oxide synthase inhibitor, ONO-1714, on inflammation-associated biliary carcinogenesis in hamsters. Carcinogenesis 30:1763-7 (2009).Read more (PubMed: 19696162) »
See all 4 publications for this product
Publishing research using ab15326? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"