Overview

  • Product nameIBMX
  • Description
    Non-specific cAMP and cGMP inhibitor
  • Biological descriptionNon-specific cAMP and cGMP inhibitor
  • Purity> 98%

Properties

  • Chemical name1-Methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
  • Molecular weight222.24
  • Chemical structureChemical Structure
  • Molecular formulaC10H14N4O2
  • CAS Number28822-58-4
  • PubChem identifier3758
  • Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in DMSO to 75 mM and in ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESCC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2
  • Source

    Synthetic

  • Research areas

    Associated products

    IBMX images

    • 1e7 3T3-L1 cells were treated for 15 minutes with 1 µM dexamethasone (ab120743) and 1 µg x mL-1 insulin (ab123768) with the addition of 50 µM forskolin (ab120058), 0.5 mM IBMX (ab120840) or 0.1 mM 8-CPT-cAMP (ab120424), extracted according to the protocol. Lysates were diluted 50-fold, and tested in duplicates (+/-SD).

    References for IBMX (ab120840)

    This product has been referenced in:
    • Levitan IB & Norman J Different effects of cAMP and cGMP derivatives on the activity of an identified neuron: biochemical and electrophysiological analysis. Brain Res 187:415-29 (1980). Read more (PubMed: 6154497) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"