Biotin Anti-ICAM1 antibody (ab7815)
Key features and details
- Biotin Rabbit polyclonal to ICAM1
- Suitable for: Sandwich ELISA
- Conjugation: Biotin
- Isotype: IgG
Overview
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Product name
Biotin Anti-ICAM1 antibody
See all ICAM1 primary antibodies -
Description
Biotin Rabbit polyclonal to ICAM1 -
Host species
Rabbit -
Conjugation
Biotin -
Tested applications
Suitable for: Sandwich ELISAmore details -
Immunogen
Full length protein corresponding to Human ICAM1.
Database link: P05362 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.065% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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Purification notes
0.2 µm filtered -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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sELISA pair antibody
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab7815 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Sandwich ELISA |
Use a concentration of 0.5 µg/ml. Can be paired for Sandwich ELISA with Mouse monoclonal [MEM-111] to ICAM1 (ab2213).
For sandwich ELISA, use this antibody as Detection at 0.5µg/ml with ab2213 as Capture. |
Notes |
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Sandwich ELISA
Use a concentration of 0.5 µg/ml. Can be paired for Sandwich ELISA with Mouse monoclonal [MEM-111] to ICAM1 (ab2213). For sandwich ELISA, use this antibody as Detection at 0.5µg/ml with ab2213 as Capture. |
Target
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Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. -
Sequence similarities
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains. -
Post-translational
modificationsMonoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. -
Cellular localization
Membrane. - Information by UniProt
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Alternative names
- Antigen identified by monoclonal antibody BB2 antibody
- BB 2 antibody
- BB2 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (7)
ab7815 has been referenced in 7 publications.
- Nan S et al. Interfering microRNA-410 attenuates atherosclerosis via the HDAC1/KLF5/IKBa/NF-?B axis. Mol Ther Nucleic Acids 24:646-657 (2021). PubMed: 33981482
- Zhang Z et al. Antioxidant and anti-inflammatory effects of DHK-medicated serum on high glucose-induced injury in endothelial cells. Mol Med Rep 16:7745-7751 (2017). PubMed: 28944884
- Zhang Q et al. Toll-like receptor 4 contributes to acute kidney injury after cardiopulmonary resuscitation in mice. Mol Med Rep 14:2983-90 (2016). Mouse . PubMed: 27510583
- Malik IA et al. Role of PECAM-1 in radiation-induced liver inflammation. J Cell Mol Med 19:2441-52 (2015). PubMed: 26177067
- Rohlena J et al. Endothelial CD81 is a marker of early human atherosclerotic plaques and facilitates monocyte adhesion. Cardiovasc Res 81:187-96 (2009). Electron Microscopy ; Human . PubMed: 18805782
- Fransson J et al. Rapid induction of apoptosis in B-cell lymphoma by functionally isolated human antibodies. Int J Cancer 119:349-58 (2006). Blocking ; Human . PubMed: 16477633
- Ohwada A et al. Acid exposure potentiates intercellular adhesion molecule-1 and e-cadherin expression on A549 alveolar lining epithelial cells. Exp Lung Res 29:389-400 (2003). ICC/IF ; Human . PubMed: 12888451