Anti-ICAM1 antibody [HM1] (ab7222)

Overview

  • Product nameAnti-ICAM1 antibody [HM1]
    See all ICAM1 primary antibodies
  • Description
    Mouse monoclonal [HM1] to ICAM1
  • Tested applicationsSuitable for: IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab7222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
ICC/IF
  • Application notesThe antibody is useful for staining of in vitro cultured cells and for staining of frozen sections by means of immunofluorescence and immunohistochemistry.
    In vitro cultured cells can be fixed with 1% paraformaldehyde and kept in PBS plus azide before staining.
  • Target

    • FunctionICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    • Sequence similaritiesBelongs to the immunoglobulin superfamily. ICAM family.
      Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen identified by monoclonal antibody BB2 antibody
      • BB 2 antibody
      • BB2 antibody
      • CD 54 antibody
      • CD_antigen=CD54 antibody
      • CD54 antibody
      • Cell surface glycoprotein P3.58 antibody
      • Human rhinovirus receptor antibody
      • ICAM 1 antibody
      • ICAM-1 antibody
      • ICAM1 antibody
      • ICAM1_HUMAN antibody
      • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody
      • Intercellular adhesion molecule 1 antibody
      • Major group rhinovirus receptor antibody
      • MALA 2 antibody
      • MALA2 antibody
      • MyD 10 antibody
      • MyD10 antibody
      • P3.58 antibody
      • Surface antigen of activated B cells, BB2 antibody
      see all

    References for Anti-ICAM1 antibody [HM1] (ab7222)

    ab7222 has not yet been referenced specifically in any publications.

    Product Wall

    This antibody works in frozen sections. We have not tried it in paraffin sections yet.

    We did a search on medline for ICAM-1 AND HM1 but could not find a specific reference to this antibody. Please let us know if you can find one or if you publish with it.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"