Anti-ICAM1 (phospho Y512) antibody (ab51033)

Overview

  • Product nameAnti-ICAM1 (phospho Y512) antibody
    See all ICAM1 primary antibodies
  • Description
    Rabbit polyclonal to ICAM1 (phospho Y512)
  • SpecificityThe antibody detects endogenous levels of ICAM-1 only when phosphorylated at tyrosine 512.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The antiserum was produced against synthesised phosphopeptide derived from ICAM-1 around the phosphorylation site of tyrosine 512 (K-K-YP-R-L)(Human)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab51033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 96 kDa (predicted molecular weight: 58 kDa).
ELISA 1/40000.

Target

  • FunctionICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. ICAM family.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen identified by monoclonal antibody BB2 antibody
    • BB 2 antibody
    • BB2 antibody
    • CD 54 antibody
    • CD_antigen=CD54 antibody
    • CD54 antibody
    • Cell surface glycoprotein P3.58 antibody
    • Human rhinovirus receptor antibody
    • ICAM 1 antibody
    • ICAM-1 antibody
    • ICAM1 antibody
    • ICAM1_HUMAN antibody
    • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody
    • Intercellular adhesion molecule 1 antibody
    • Major group rhinovirus receptor antibody
    • MALA 2 antibody
    • MALA2 antibody
    • MyD 10 antibody
    • MyD10 antibody
    • P3.58 antibody
    • Surface antigen of activated B cells, BB2 antibody
    see all

Anti-ICAM1 (phospho Y512) antibody images

  • All lanes : Anti-ICAM1 (phospho Y512) antibody (ab51033) at 1/500 dilution

    Lane 1 : Hela cells treated with TNF alpha with immunizing peptide
    Lane 2 : Hela cells treated with TNF alpha


    Predicted band size : 58 kDa
    Observed band size : 96 kDa (why is the actual band size different from the predicted?)

References for Anti-ICAM1 (phospho Y512) antibody (ab51033)

ab51033 has not yet been referenced specifically in any publications.

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