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Anti-ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268)

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Overview

Product name

Anti-ICAM2 antibody [CBR-IC2/2] (Biotin)
See all ICAM2 products (15) ...

Description

Mouse monoclonal [CBR-IC2/2] to ICAM2 (Biotin)

Conjugation

Biotin

Specificity

This antibody recognizes human CD10, also known as intercellular adhesion molecule 2 (ICAM 2).

Tested applications

Flow Cytmore details

Cross reactivity

Reacts with

Human

Immunogen

Transfected COS cells expressing ICAM 2 cDNA.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Purification notes

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Primary antibody notes

Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA 1

Clonality

Monoclonal

Clone number

CBR-IC2/2

Myeloma

P3x63-Ag8.653

Isotype

IgG2a

  • Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268)Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab35268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

Flow Cyt: 1/1. Use 10µl of neat antibody to label 106 cells in 100µl.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Cellular localization

Membrane; Single-pass type I membrane protein

Alternative names

  • Intercellular adhesion molecule 2 precursor antibody
  • CD 10 antibody
  • CD102 antibody
  • CD102 antigen antibody
  • ICAM 2 antibody
  • Ly60 antibody
  • Membrane metallo endopeptidase antibody
see all

Database links

Anti-ICAM2 antibody [CBR-IC2/2] (Biotin) images:

  Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268)

Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268)

ab35268 neat, staining peripheral blood monocytes in a FACS assay. 10µl of neat antibody to label 106 cells in 100µl.

References for Anti-ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268)

This product has been referenced in:

  • Issekutz ACet al. Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration. J Leukoc Biol 65:117-26 (1999).Read more (PubMed: 9886254) »
  • Hart DN & Prickett TC Intercellular adhesion molecule-2 (ICAM-2) expression on human dendritic cells. Cell Immunol 148:447-54 (1993).Read more (PubMed: 8098673) »

See all 3 publications for this product

Publishing research using ab35268? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"