ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268)

Product Name 

ICAM2 antibody [CBR-IC2/2] (Biotin)

Product type 

Primary antibodies

Description 

Mouse monoclonal [CBR-IC2/2] to ICAM2 (Biotin)

Immunogen 

Transfected COS cells expressing ICAM 2 cDNA.

Reacts with 
(species key)

Hu

Specificity 

This antibody recognizes human CD10, also known as intercellular adhesion molecule 2 (ICAM 2).

Tested applications 
(see key)

Flow Cyt

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
Flow Cyt: 1/1. Use 10µl of neat antibody to label 10⁶ cells in 100µl.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Type I membrane protein

Research areas 

Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Mesenchymal Stem Cells >> Surface Molecules
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Cell Type Markers >> CD >> Adhesion
Immunology >> Adaptive Immunity >> B Cells >> CD

Relevance 

ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA 1

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

CBR-IC2/2

Myeloma 

P3x63-Ag8.653

Isotype 

IgG2a

Purity 

Protein G purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Form 

Liquid

Conjugation 

Biotin

Concentration 

0.100 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

See below for ICAM2 antibody [CBR-IC2/2] (Biotin) images, references, products related to ab35268 and other tools.

ICAM2 antibody [CBR-IC2/2] (Biotin) images:

References for ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268)

  This clone has been used in: (two most recent references)

Issekutz AC et al. Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration. J Leukoc Biol 65:117-26 (1999). PubMed: 9886254

Hart DN & Prickett TC Intercellular adhesion molecule-2 (ICAM-2) expression on human dendritic cells. Cell Immunol 148:447-54 (1993). PubMed: 8098673

See all 3 publication references for this product.


If you publish research using ab35268 please let us know so that we can cite the reference on this datasheet.

Customer reviews (feedback) regarding ICAM2 antibody [CBR-IC2/2] (Biotin)

Customer FAQs regarding ICAM2 antibody [CBR-IC2/2] (Biotin)

Protocols for ICAM2 antibody [CBR-IC2/2] (Biotin)

Price and availability of products related to ICAM2 antibody [CBR-IC2/2] (Biotin)

ICAM2 antibody [CBR-IC2/2] (Biotin) - related products: