![Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268) image](#ab35268.gif)
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Products:Immunology >> Adaptive Immunity >> B Cells >> CD
Overview
Product name
Anti-ICAM2 antibody [CBR-IC2/2] (Biotin)
See all ICAM2 products (15) ...
Description
Mouse monoclonal [CBR-IC2/2] to ICAM2 (Biotin)
Conjugation
Biotin
Specificity
This antibody recognizes human CD10, also known as intercellular adhesion molecule 2 (ICAM 2).
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
Transfected COS cells expressing ICAM 2 cDNA.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Primary antibody notes
Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA 1
Clonality
Monoclonal
Clone number
CBR-IC2/2
Myeloma
P3x63-Ag8.653
Isotype
IgG2a
Research areas
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Mesenchymal Stem Cells >> Surface Molecules
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Cell Type Markers >> CD >> Adhesion
Immunology >> Adaptive Immunity >> B Cells >> CD
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Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268)
![Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268) image](/ps/datasheet/Images/35/ab35268/ab35268.gif)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab35268 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
Flow Cyt
Application notes
Flow Cyt: 1/1. Use 10µl of neat antibody to label 106 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Cellular localization
Membrane; Single-pass type I membrane protein
Alternative names
- Intercellular adhesion molecule 2 precursor antibody
- CD 10 antibody
- CD102 antibody
see all
Database links
- Entrez Gene: 3384 Human
- Omim: 146630 Human
- SwissProt: P13598 Human
Anti-ICAM2 antibody [CBR-IC2/2] (Biotin) images:
Flow Cytometry / FACS - CD10 antibody [ICAM-2] (Biotin) (ab35268)
ab35268 neat, staining peripheral blood monocytes in a FACS assay. 10µl of neat antibody to label 106 cells in 100µl.
References for Anti-ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268)
This product has been referenced in:
- Issekutz ACet al. Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration. J Leukoc Biol 65:117-26 (1999).Read more (PubMed: 9886254) »
- Hart DN & Prickett TC Intercellular adhesion molecule-2 (ICAM-2) expression on human dendritic cells. Cell Immunol 148:447-54 (1993).Read more (PubMed: 8098673) »
See all 3 publications for this product
Publishing research using ab35268? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"