Overview

  • Product nameAnti-ICAM2 antibody [mIC2/4 (3C4)] (FITC)
    See all ICAM2 primary antibodies
  • Description
    Rat monoclonal [mIC2/4 (3C4)] to ICAM2 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • SpecificityMurine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA1.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    COS cells transfected with murine ICAM2.

  • General notes


    Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Primary antibody notesClone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.
  • ClonalityMonoclonal
  • Clone numbermIC2/4 (3C4)
  • MyelomaP3x63-Ag8.653
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab23842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/1 - 1/10.

Neat - 1/10. Use 10µl of the suggested working dilution to label 106 cells in 100µl.





ab18446-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
  • Cellular localizationMembrane; Single-pass type I membrane protein
  • Database links
  • Alternative names
    • CD102 antibody
    • CD102 antigen antibody
    • ICAM 2 antibody
    • Intercellular adhesion molecule 2 antibody
    • Ly60 antibody
    see all

References for Anti-ICAM2 antibody [mIC2/4 (3C4)] (FITC) (ab23842)

This product has been referenced in:

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab23842.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"