Overview

  • Product nameAnti-ICAM3 antibody [MEM-171] (Biotin)
    See all ICAM3 primary antibodies
  • Description
    Mouse monoclonal [MEM-171] to ICAM3 (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation: Human granulocytes.

  • EpitopeD2 domain of ICAM3.
  • General notes

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

Properties

Applications

Our Abpromise guarantee covers the use of ab21895 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/500. ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.

Target

  • FunctionICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. ICAM family.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues.
    N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD50 antibody
    • CDW 50 antibody
    • CDw50 antibody
    • ICAM 3 antibody
    • ICAM-3 antibody
    • ICAM-R antibody
    • ICAM3 antibody
    • ICAM3_HUMAN antibody
    • ICAMR antibody
    • Intercellular adhesion molecule 3 antibody
    see all

References for Anti-ICAM3 antibody [MEM-171] (Biotin) (ab21895)

This product has been referenced in:
  • Valignat MP  et al. Lymphocytes can self-steer passively with wind vane uropods. Nat Commun 5:5213 (2014). Read more (PubMed: 25323331) »
  • Linnebacher M  et al. Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO). J Biomed Biotechnol 2010:841451 (2010). Read more (PubMed: 20339516) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"