Overview

  • Product nameAnti-IDH3B antibody
    See all IDH3B primary antibodies
  • Description
    Goat polyclonal to IDH3B
  • SpecificityThis antibody is expected to recognize isoform a (NP_008830.2) and isoform b (NP_777280.1).
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Pig
    Predicted to work with: Cynomolgus Monkey, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human IDH3B aa 33-46 (internal sequence) (Cysteine residue).
    Sequence:

    HAASRSQAEDVRVE


    Database link: O43837

  • Positive control
    • Human skeletal muscle lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab118287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 42 kDa).
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:1,000

Target

  • Involvement in diseaseDefects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similaritiesBelongs to the isocitrate and isopropylmalate dehydrogenases family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11043 antibody
    • H-IDHB antibody
    • Idh3B antibody
    • IDH3B_HUMAN antibody
    • Isocitrate dehydrogenase [NAD] subunit beta antibody
    • Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial antibody
    • isocitrate dehydrogenase 3, beta subunit antibody
    • Isocitric dehydrogenase antibody
    • Isocitric dehydrogenase subunit beta antibody
    • MGC903 antibody
    • mitochondrial antibody
    • NAD(+)-specific ICDH antibody
    • NAD(+)-specific ICDH subunit beta antibody
    • NAD+-specific isocitrate dehydrogenase b subunit antibody
    • NAD+-specific isocitrate dehydrogenase beta antibody
    • OTTHUMP00000030023 antibody
    • OTTHUMP00000030024 antibody
    • RP46 antibody
    see all

Anti-IDH3B antibody images

  • Anti-IDH3B antibody (ab118287) at 0.1 µg/ml + Pig Heart lysate at 35 µg

    Predicted band size : 42 kDa
  • All lanes : Anti-IDH3B antibody (ab118287) at 2 µg/ml

    Lane 1 : Mouse Heart lysate
    Lane 2 : Mouse Muscle lysate

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 42 kDa
  • Anti-IDH3B antibody (ab118287) at 0.3 µg/ml + Human skeletal muscle lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 42 kDa

References for Anti-IDH3B antibody (ab118287)

ab118287 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"