Overview

  • Product nameAnti-IFITM1 antibody
    See all IFITM1 primary antibodies
  • Description
    Rabbit polyclonal to IFITM1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids of Human IFITM1 (NP_003632.3).

  • Positive control
    • Human thymus and tonsil tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab117519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2.5 - 5 µg/ml. Predicted molecular weight: 14 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 10 µg/ml.

Target

  • FunctionIFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
  • Sequence similaritiesBelongs to the CD225 family.
  • Post-translational
    modifications
    Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9-27 antibody
    • CD 225 antibody
    • CD 225 antigen antibody
    • CD225 antibody
    • CD225 antigen antibody
    • Dispanin subfamily A member 2a antibody
    • DSPA2a antibody
    • IFI 17 antibody
    • IFI17 antibody
    • IFITM1 antibody
    • IFM1_HUMAN antibody
    • Interferon induced protein 17 antibody
    • interferon induced transmembrane protein 1 (9-27) antibody
    • Interferon induced transmembrane protein 1 antibody
    • Interferon inducible protein 9-27 antibody
    • Interferon-induced protein 17 antibody
    • Interferon-induced transmembrane protein 1 antibody
    • Interferon-inducible protein 9-27 antibody
    • Leu 13 antibody
    • Leu 13 antigen antibody
    • Leu-13 antigen antibody
    • LEU13 antibody
    see all

Anti-IFITM1 antibody images

  • ab117519, at 10 µg/ml, staining IFITM1 in in Formalin-fixed, Paraffin-embedded Human thymus tissue by Immunohistochemistry.
  • ab117519, at 10 µg/ml, staining IFITM1 in in Formalin-fixed, Paraffin-embedded Human tonsil tissue by Immunohistochemistry.

References for Anti-IFITM1 antibody (ab117519)

ab117519 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab117519.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"