Overview

  • Product nameAnti-IFNAR1 antibody
    See all IFNAR1 primary antibodies
  • Description
    Rabbit polyclonal to IFNAR1
  • Specificityab91466 recognises isoform 2
  • Tested applicationsSuitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the center region of Human IFNAR1 conjugated to KLH (NP_000620.2).

  • Positive control
    • K562 cell line lysates.
  • General notes

    This antibody was used as a capture antibody in sELISA and was paired with ab10739 as detection antibody. Abreview 24657.

     

Properties

Applications

Our Abpromise guarantee covers the use of ab91466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAssociates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    • Tissue specificityIFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
    • Sequence similaritiesBelongs to the type II cytokine receptor family.
      Contains 3 fibronectin type-III domains.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha type antiviral protein antibody
      • AVP antibody
      • Beta type antiviral protein antibody
      • CRF2-1 antibody
      • Cytokine receptor class-II member 1 antibody
      • Cytokine receptor family 2 member 1 antibody
      • IFN alpha REC antibody
      • IFN alpha receptor antibody
      • IFN alpha/beta Receptor alpha antibody
      • IFN beta receptor antibody
      • IFN-alpha/beta receptor 1 antibody
      • IFN-R-1 antibody
      • IFNAR antibody
      • Ifnar1 antibody
      • IFNBR antibody
      • IFRC antibody
      • INAR1_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 1 antibody
      • Interferon alpha/beta receptor 1 antibody
      • Interferon alpha/beta receptor alpha chain antibody
      • Interferon beta receptor 1 antibody
      • Type I interferon receptor 1 antibody
      see all

    Anti-IFNAR1 antibody images

    • Anti-IFNAR1 antibody (ab91466) at 1/100 dilution + K562 cell line lysates at 35 µg

      Predicted band size : 50 kDa

    References for Anti-IFNAR1 antibody (ab91466)

    ab91466 has not yet been referenced specifically in any publications.

    Product Wall

    Abreviews
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application ELISA
    Sample Human Recombinant protein (IFNAR1 Recombinant Protein and K562 cell lysates)
    Specification IFNAR1 Recombinant Protein and K562 cell lysates
    Blocking step BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 0.05% · Temperature: 4°C
    Type Sandwich (Detection)
    Username

    Christopher Leung

    Verified customer

    Submitted Aug 12 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"