Anti-IFNAR1 (phospho S535 + S539) antibody (ab30571)

Overview

  • Product nameAnti-IFNAR1 (phospho S535 + S539) antibody
    See all IFNAR1 primary antibodies
  • Description
    Rabbit polyclonal to IFNAR1 (phospho S535 + S539)
  • SpecificitySpecific for IFNAR1 protein phosphorylated at Ser535,539 in Western blots of human brain extracts.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-535,539 of human Interferon-alpha Receptor, Type I, Subunit I (IFNAR1).

Properties

Applications

Our Abpromise guarantee covers the use of ab30571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000. Predicted molecular weight: 110-130 kDa.
    Note: the molecular weight of the IFNNAR1 varies with cell line
    (different levels of glycosylation) in 293 and HeLa Cells; the mature form is ~110 - 130k.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAssociates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    • Tissue specificityIFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
    • Sequence similaritiesBelongs to the type II cytokine receptor family.
      Contains 3 fibronectin type-III domains.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha type antiviral protein antibody
      • AVP antibody
      • Beta type antiviral protein antibody
      • CRF2-1 antibody
      • Cytokine receptor class-II member 1 antibody
      • Cytokine receptor family 2 member 1 antibody
      • IFN alpha REC antibody
      • IFN alpha receptor antibody
      • IFN alpha/beta Receptor alpha antibody
      • IFN beta receptor antibody
      • IFN-alpha/beta receptor 1 antibody
      • IFN-R-1 antibody
      • IFNAR antibody
      • Ifnar1 antibody
      • IFNBR antibody
      • IFRC antibody
      • INAR1_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 1 antibody
      • Interferon alpha/beta receptor 1 antibody
      • Interferon alpha/beta receptor alpha chain antibody
      • Interferon beta receptor 1 antibody
      • Type I interferon receptor 1 antibody
      see all

    Anti-IFNAR1 (phospho S535 + S539) antibody images

    References for Anti-IFNAR1 (phospho S535 + S539) antibody (ab30571)

    ab30571 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab30571.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"