Overview

  • Product name
    Anti-IFT172 antibody
  • Description
    Rabbit polyclonal to IFT172
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to internal sequence amino acids 1490-1599 of Human IFT172.

  • Positive control
    • Human lateral ventricle tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
  • Sequence similarities
    Belongs to the IFT172 family.
    Contains 14 TPR repeats.
    Contains 9 WD repeats.
  • Cellular localization
    Cell projection > cilium.
  • Information by UniProt
  • Database links
    • Alternative names
      • IF172_HUMAN antibody
      • ift172 antibody
      • Intraflagellar transport 172 homolog (Chlamydomonas) antibody
      • Intraflagellar transport protein 172 homolog antibody
      • Osm 1 antibody
      • Selective LIM binding factor homolog antibody
      • SLB antibody
      • Wim antibody
      • Wimple homolog antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IFT172 antibody (ab122879)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IFT172 antibody (ab122879)
      ab122879 at 1/50 dilution staining IFT172 in paraffin-embedded Human lateral ventricle tissue by Immunohistochemistry.

    References

    This product has been referenced in:
    • Halbritter J  et al. Defects in the IFT-B Component IFT172 Cause Jeune and Mainzer-Saldino Syndromes in Humans. Am J Hum Genet 93:915-25 (2013). Human . Read more (PubMed: 24140113) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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