Anti-IgE antibody, prediluted (ab75673)

Overview

  • Product nameAnti-IgE antibody, prediluted
    See all IgE primary antibodies
  • Description
    Rabbit polyclonal to IgE, prediluted
  • SpecificityThis antibody recognizes IgE, epsilon heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), mu (IgM), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length IgE isolated from a pool of normal human sera.

  • Positive control
    • Human Tonsil tissue
  • General notes


    This antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas.

Properties

  • FormPrediluted
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: 0.5 mol/L Tris HCl, pH 7.6, and containing a stabilizing protein
  • Concentration information loading...
  • PurityProtein A purified
  • Primary antibody notesThis antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Ready to use.

Target

  • RelevanceIgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
  • Cellular localizationCell Membrane
  • Database links
  • Alternative names
    • Igh2 antibody
    • IGHE antibody
    • IGHEP1 antibody
    • Immunoglobulin heavy constant epsilon antibody

Anti-IgE antibody, prediluted images

  • Formalin-fixed, paraffin-embedded human tonsil stained with ab75673, using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of IgE-secreting cells.

References for Anti-IgE antibody, prediluted (ab75673)

ab75673 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (duodenum - normal and celiac dz)
Specification duodenum - normal and celiac dz
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: EDTA pH9.0, 100C 20 min
Permeabilization No
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Submitted Dec 09 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"