Overview

  • Product name
    Anti-IgE antibody [XTE4]
    See all IgE primary antibodies
  • Description
    Mouse monoclonal [XTE4] to IgE
  • Host species
    Mouse
  • Specificity
    Epsilon chain specific
  • Tested applications
    Suitable for: ELISA, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human IgE. IgE from myelomatous human serum

  • General notes

    Concentration varies from lot to lot and can be provided on request.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. We would recommend antibody ab195580 as a replacement.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 0.15M Sodium Chloride, 10mM Tris. pH 7.5
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    XTE4
  • Myeloma
    Sp2/0
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab7382 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1e+006. Can be used for the detection of total IgE level and IgE antibodies in ELISA.
WB Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution. PubMed: 21307287

Target

  • Relevance
    IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • Igh2 antibody
    • IGHE antibody
    • IGHEP1 antibody
    • Immunoglobulin heavy constant epsilon antibody

References

This product has been referenced in:
  • Palaniyandi S  et al. CD23-Dependent Transcytosis of IgE and Immune Complex across the Polarized Human Respiratory Epithelial Cells. J Immunol 186:3484-96 (2011). WB, ICC/IF, ELISA ; Human . Read more (PubMed: 21307287) »

See 1 Publication for this product

Customer reviews and Q&As

Thank you for contacting us and sorry for the delay in getting back to you.

In answer to your questions:

1. Yes, I believe the antibody ab7382 should be suitable for the experiment you have described, however, as we have not perfor...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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