• Product nameAnti-IGF2 antibody
    See all IGF2 primary antibodies
  • Description
    Rabbit polyclonal to IGF2
  • Tested applicationsSuitable for: Sandwich ELISA, WB, Neutralising, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human IGF2. 67 amino acid residues



Our Abpromise guarantee covers the use of ab18954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use a concentration of 0.5 µg/ml. Can be paired for Sandwich ELISA with Rat monoclonal [RM0100-3J42] to IGF2 (ab86485). For sandwich ELISA, use this antibody as Detection at 0.5µg/ml with Ab86485 as Capture.
WB Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 20 kDa.
Neutralising Use a concentration of 0.5 - 4 µg/ml.
ELISA Use a concentration of 2 - 3 µg/ml.


  • FunctionThe insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
    Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
  • Involvement in diseaseEpigenetic changes of DNA hypomethylation in IGF2 are a cause of Silver-Russell syndrome (SIRS) [MIM:180860]. SIRS is a clinically heterogeneous condition characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations.
  • Sequence similaritiesBelongs to the insulin family.
  • Post-translational
    O-glycosylated with a core 1 or possibly core 8 glycan.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C11orf43 antibody
    • IGF 2 antibody
    • IGF II antibody
    • IGF-II antibody
    • IGF2 antibody
    • IGF2_HUMAN antibody
    • IGFII antibody
    • INSIGF antibody
    • insulin like growth factor 2 (somatomedin A) antibody
    • Insulin like Growth Factor 2 antibody
    • Insulin like growth factor II antibody
    • Insulin like growth factor II precursor antibody
    • Insulin like growth factor type 2 antibody
    • pp9974 antibody
    • Preptin antibody
    • putative insulin like growth factor II associated protein antibody
    • Somatomedin A antibody
    • Somatomedin-A antibody
    see all

Anti-IGF2 antibody images

  • Predicted band size : 20 kDa

    Western blot analysis of IGF-II using recombinant human IGF-II.

    Lane 1;50ng

    Lane 2;250 ng

    Lane 3;500 ng

  • Standard Curve for IGF2 (Analyte: ab9575) dilution range 1pg/ml to 1ug/ml using Capture Antibody Rat monoclonal [RM0100-3J42] to IGF2 (ab86485) at 1ug/ml and Detector Antibody Rabbit polyclonal to IGF2 (ab18954) at 0.5ug/ml.

References for Anti-IGF2 antibody (ab18954)

ab18954 has not yet been referenced specifically in any publications.

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