Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab4249 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
  • Application notesIP: 1/500. Precipitates >90% of 10ng IGFBP 1.
    WB: 1/1000. Detects 10ng SDS denatured human IGFBP 1. Predicted molecular weight: 30 kDa.
    Not tested in other applications.

    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
    • Sequence similaritiesContains 1 IGFBP N-terminal domain.
      Contains 1 thyroglobulin type-1 domain.
    • Post-translational
      modifications
      Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • AFBP antibody
      • Alpha pregnancy associated endometrial globulin antibody
      • Amniotic fluid binding protein antibody
      • Binding protein 25 antibody
      • Binding protein 26 antibody
      • Binding protein 28 antibody
      • Growth hormone independent binding protein antibody
      • hIGFBP 1 antibody
      • hIGFBP1 antibody
      • IBP 1 antibody
      • IBP-1 antibody
      • IBP1 antibody
      • IBP1_HUMAN antibody
      • IGF binding protein 1 antibody
      • IGF BP25 antibody
      • IGF-binding protein 1 antibody
      • IGFBP 1 antibody
      • IGFBP-1 antibody
      • IGFBP1 antibody
      • Insulin like growth factor binding protein 1 antibody
      • Insulin-like growth factor-binding protein 1 antibody
      • Placental protein 12 antibody
      • PP 12 antibody
      • PP12 antibody
      see all

    References for Anti-IGFBP1 antibody (ab4249)

    ab4249 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab4249.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"