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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Concentration information loading...
Purity Immunogen affinity purified
Purification notes IgG fraction of culture supernatant purified by Protein A/G affinity chromatography and 0.2 µm filtered.
Primary antibody notes ab86461 was produced from a hybridoma (mouse myeloma fused with
spleen cells from an immunized rat).
Clone number RM0096-11B16
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Use under non reducing condition. Predicted molecular weight: 32 kDa.
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Tissue specificity Expressed by most tissues. Present in plasma.
Sequence similarities Contains 1 IGFBP N-terminal domain. Contains 1 thyroglobulin type-1 domain.
Developmental stage IGFBP3 levels are higher during extrauterine life and peak during puberty.
Domain The thyroglobulin type-1 domain mediates interaction with HN.
Post-translational modifications Phosphorylation sites are present in the extracelllular medium.
Cellular localization Secreted.
Information by UniProt
Acid stable subunit of the 140 K IGF complex antibody
Binding protein 29 antibody
Binding protein 53 antibody
Anti-IGFBP3 antibody [RM0096-11B16] images
References for Anti-IGFBP3 antibody [RM0096-11B16] (ab86461)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"