Overview

  • Product nameAnti-IGFBP4 antibody
    See all IGFBP4 primary antibodies
  • Description
    Rabbit polyclonal to IGFBP4
  • SpecificityCross reactivity: IGFBP 1 = 1%, IGFBP 2 = 50%, IGFBP 3 = < 0.2%, IGFBP 5 = < 0.1%.
  • Tested applicationsSuitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Cow, Human, Pig
  • Immunogen

    HPLC purified IGFBP 4 isolated from conditioned medium from the human glioblastoma cell line, T98G.

Properties

Applications

Our Abpromise guarantee covers the use of ab4253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
WB
  • Application notesIP: 4µl immunoprecipitated >90% of 10ng IGFBP 4 from 500µl concentrated serum free T98G culture supernatant.
    WB: 1/1000. Detects 1ng SDS-denatured human IGFBP 4 in concentrated serum free T98G culture supernatant. Predicted molecular weight: 24 kDa.
    Not tested in other applications.

    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
    • Sequence similaritiesContains 1 IGFBP N-terminal domain.
      Contains 1 thyroglobulin type-1 domain.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • AI875747 antibody
      • BP 4 antibody
      • BP4 antibody
      • Deb2 antibody
      • HT29 IGFBP antibody
      • IBP 4 antibody
      • IBP-4 antibody
      • IBP4 antibody
      • IBP4_HUMAN antibody
      • IGF binding protein 4 antibody
      • IGF-binding protein 4 antibody
      • IGF-BP4 antibody
      • IGFBP 4 antibody
      • IGFBP-4 antibody
      • IGFBP4 antibody
      • Insulin Like Growth Factor Binding Protein 4 antibody
      • Insulin-like growth factor-binding protein 4 antibody
      see all

    References for Anti-IGFBP4 antibody (ab4253)

    This product has been referenced in:
    • Pan H  et al. Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo. PLoS One 7:e48799 (2012). WB . Read more (PubMed: 23152806) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. The immunogen for ab4253 was the full-length purified IGFBP-4 isolated from the human glioblastoma cell line, T98G. Unfortunately we do not sell this protein. The literature indicates that numerous proteolytic fragme...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"