Anti-IGFBP5 antibody [RM0097-12C23] (ab86463)

Overview

• Product nameAnti-IGFBP5 antibody [RM0097-12C23]
  See all IGFBP5 primary antibodies
• Description
  Rat monoclonal [RM0097-12C23] to IGFBP5
• SpecificityNo cross reactivity seen to other mouse IGFBP proteins.
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Mouse
  
• Immunogen

  Recombinant mouse IGFBP5

• General notes

  
  

  ab86463 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesIgG fraction of culture supernatant purified by Protein A/G affinity chromatography and 0.2 µm filtered.
• Primary antibody notesab86463 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
• ClonalityMonoclonal
• Clone numberRM0097-12C23
• IsotypeIgG2
• Research areas
  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Other

  • Signal Transduction
  • Growth Factors/Hormones
  • Insulin / Insulin-like

Associated products

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

Applications

Target

• FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
• Tissue specificityOsteosarcoma, and at lower levels in liver, kidney and brain.
• Sequence similaritiesContains 1 IGFBP N-terminal domain.
  Contains 1 thyroglobulin type-1 domain.
• Cellular localizationSecreted.

• Target information above from: UniProt accession P24593 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 16011 Mouse
  • SwissProt: Q07079 Mouse
  • Unigene: 405761 Mouse
• Alternative names
  • IBP 5 antibody
  • IBP-5 antibody
  • IBP5 antibody

  • IBP5_HUMAN antibody
  • IGF binding protein 5 antibody
  • IGF BP5 antibody
  • IGF-binding protein 5 antibody
  • IGFBP 5 antibody
  • IGFBP-5 antibody
  • IGFBP5 antibody
  • Insulin like growth factor binding protein 5 antibody
  • Insulin-like growth factor-binding protein 5 antibody

  see all