Anti-IGFBP5 antibody [RM0097-12C23] (ab86463)

Overview

• Product name
  Anti-IGFBP5 antibody [RM0097-12C23]
  See all IGFBP5 primary antibodies
• Description
  Rat monoclonal [RM0097-12C23] to IGFBP5
• Specificity
  No cross reactivity seen to other mouse IGFBP proteins.
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Mouse
  
• Immunogen

  Recombinant mouse IGFBP5

• General notes

  
  

  ab86463 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage buffer
  Preservative: None
  Constituents: PBS
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  IgG fraction of culture supernatant purified by Protein A/G affinity chromatography and 0.2 µm filtered.
• Primary antibody notes
  ab86463 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
• Clonality
  Monoclonal
• Clone number
  RM0097-12C23
• Isotype
  IgG2
• Research areas
  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Other

  • Signal Transduction
  • Growth Factors/Hormones
  • Insulin / Insulin-like

Associated products

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

Applications

Target

• Function
  IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
• Tissue specificity
  Osteosarcoma, and at lower levels in liver, kidney and brain.
• Sequence similarities
  Contains 1 IGFBP N-terminal domain.
  Contains 1 thyroglobulin type-1 domain.
• Cellular localization
  Secreted.

• Target information above from: UniProt accession P24593 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 16011 Mouse
  • SwissProt: Q07079 Mouse
  • Unigene: 405761 Mouse
• Alternative names
  • IBP 5 antibody
  • IBP-5 antibody
  • IBP5 antibody

  • IBP5_HUMAN antibody
  • IGF binding protein 5 antibody
  • IGF BP5 antibody
  • IGF-binding protein 5 antibody
  • IGFBP 5 antibody
  • IGFBP-5 antibody
  • IGFBP5 antibody
  • Insulin like growth factor binding protein 5 antibody
  • Insulin-like growth factor-binding protein 5 antibody

  see all

Protocols

• Western blot protocols