Overview

  • Product name
  • Description
    Rabbit polyclonal to IGFBP6
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to an internal sequence of Human IGFBP6.

Properties

Applications

Our Abpromise guarantee covers the use of ab112491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa.

Target

  • Function
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • Sequence similarities
    Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • Post-translational
    modifications
    O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • IBP 6 antibody
    • IBP-6 antibody
    • IBP6 antibody
    • IBP6_HUMAN antibody
    • IGF binding protein 6 antibody
    • IGF-binding protein 6 antibody
    • IGFBP 6 antibody
    • IGFBP-6 antibody
    • IGFBP6 antibody
    • Insulin like growth factor binding protein 6 antibody
    • Insulin-like growth factor-binding protein 6 antibody
    see all

Images

  • All lanes : Anti-IGFBP6 antibody (ab112491)

    Lane 1 : Rat liver tissue lysate
    Lane 2 : Rat pancreas tissue lysate
    Lane 3 : Rat brain tissue lysate
    Lane 4 : Rat kidney tissue lysate
    Lane 5 : SMMC whole cell lysate


    Predicted band size : 25 kDa
    Observed band size : 25 kDa

References

ab112491 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab112491.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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