Recombinant
RabMAb

Anti-IGFBP7 antibody [EPR11912(B)] (ab171085)

Overview

  • Product name
    Anti-IGFBP7 antibody [EPR11912(B)]
    See all IGFBP7 primary antibodies
  • Description
    Rabbit monoclonal [EPR11912(B)] to IGFBP7
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IF, Flow Cytmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human IGFBP7 aa 100-200 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q16270

  • Positive control
    • SW480, 293T and MCF7 cell lysates; Human pancreas and prostate tissues; MCF7 cells; 293T cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab171085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 29 kDa.
IHC-P 1/50 - 1/100.
ICC/IF 1/250 - 1/500.
Flow Cyt 1/250 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
    • Sequence similarities
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 IGFBP N-terminal domain.
      Contains 1 Kazal-like domain.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • AGM antibody
      • Angiomodulin antibody
      • FSTL2 antibody
      • IBP-7 antibody
      • IBP7 antibody
      • IBP7_HUMAN antibody
      • IGF binding protein 7 antibody
      • IGF-binding protein 7 antibody
      • IGFBP rP1 antibody
      • IGFBP-7 antibody
      • IGFBP-rP1 antibody
      • IGFBP7 antibody
      • IGFBPRP1 antibody
      • Insulin like growth factor binding protein 7 antibody
      • Insulin-like growth factor-binding protein 7 antibody
      • MAC25 antibody
      • MAC25 protein antibody
      • PGI2 stimulating factor antibody
      • PGI2-stimulating factor antibody
      • Prostacyclin stimulating factor antibody
      • Prostacyclin-stimulating factor antibody
      • PSF antibody
      • RAMSVPS antibody
      • TAF antibody
      • Tumor-derived adhesion factor antibody
      see all

    Images

    • All lanes : Anti-IGFBP7 antibody [EPR11912(B)] (ab171085) at 1/1000 dilution

      Lane 1 : SW480 cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 29 kDa
    • Flow cytometric analysis of permeabilized 293T cells labeling IGFBP7 with ab171085 at 1/250 dilution (red) compared to a rabbit IgG negative control (green).

    • Immunofluorescent analysis of MCF7 cells labeling IGFBP7 with ab171085 at 1/250 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human prostate tissue labeling IGFBP7 with ab171085 at 1/50 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human pancreas tissue labeling IGFBP7 with ab171085 at 1/50 dilution.

    References

    This product has been referenced in:
    • Sill M  et al. Protein Profiling Gastric Cancer and Neighboring Control Tissues Using High-Content Antibody Microarrays. Microarrays (Basel) 5:N/A (2016). IHC . Read more (PubMed: 27600085) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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