Overview

  • Product name
  • Description
    Rabbit polyclonal to IGLL1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 130-213 of Human IGLL1 (Uniprot ID: P15814).

  • Positive control
    • THP1 whole cell lysate; Human colon epithelium lymphocyte tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. 10mM Citrate buffer

Target

  • Function
    Critical for B-cell development.
  • Tissue specificity
    Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
  • Involvement in disease
    Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:613500]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
  • Sequence similarities
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 14.1 antibody
    • AGM2 antibody
    • CD179 antigen-like family member B antibody
    • CD179b antibody
    • CD179b antigen antibody
    • Ig lambda 5 antibody
    • Ig lambda-5 antibody
    • IGL1 antibody
    • IGL5 antibody
    • IGLJ14.1 antibody
    • IGLL antibody
    • Igll1 antibody
    • IGLL1_HUMAN antibody
    • IGO antibody
    • IGVPB antibody
    • Immunoglobulin lambda like polypeptide 1 precursor antibody
    • Immunoglobulin lambda-like polypeptide 1 antibody
    • Immunoglobulin omega polypeptide antibody
    • Immunoglobulin omega polypeptide chain antibody
    • Immunoglobulin related protein 14.1 antibody
    • Immunoglobulin-related protein 14.1 antibody
    • Lambda5 antibody
    • Pre B lymphocyte specific protein 2 antibody
    • VPREB2 antibody
    see all

Images

  • Anti-IGLL1 antibody (ab154517) at 1/1000 dilution + THP1 whole cell lysate at 30 µg

    Predicted band size: 23 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human colon epithelium lymphocyte tissue labeling IGLL1 with ab154517 at 1/250 dilution.

References

ab154517 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154517.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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