Overview

  • Product name
    Anti-IKIP antibody - C-terminal
    See all IKIP primary antibodies
  • Description
    Rabbit polyclonal to IKIP - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IKIP aa 318-345 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q70UQ0

  • Positive control
    • Jurkat cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab173666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 39 kDa.

Target

  • Relevance
    IKIP (I kappa B kinase interacting protein)is located on chromosome 12 in close proximity to APAF1 (apoptotic protease-activating factor-1). IKIP was originally cloned from a yeast two hybrid screening as an IKK2 interacting protein. IKIP and APAF1 share a common 488 bp promoter from which the two genes are transcribed in opposite directions, presumably in a co-regulated manner. Three IKIP transcripts are generated by differential splicing and alternative exon usage and show no significant homology to other genes. IKIP is expressed predominantly in the lung, kidney, spleen, thymus and skeletal muscle. Like APAF1, expression of IKIP is enhanced by ?-irradiation, in a p53-dependent manner. When transfected into endothelial cells IKIP promotes apoptosis suggesting that it plays a role in the cell death process as well as NF-?B regulation.
  • Database links
  • Alternative names
    • FLJ31051 antibody
    • I kappa B kinase interacting protein antibody
    • IKBIP antibody
    • IKBKB interacting protein antibody
    • IKIP1 antibody
    • IKIP2 antibody
    • IKIP3 antibody
    • IKK interacting protein antibody
    • Inhibitor of nuclear factor kappa B kinase interacting protein antibody
    see all

Images

  • Anti-IKIP antibody - C-terminal (ab173666) at 1/100 dilution + Jurkat cell line lysates at 35 µg

    Predicted band size : 39 kDa

References

ab173666 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab173666.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up